Ontology highlight
ABSTRACT:
SUBMITTER: Yukimoto N
PROVIDER: S-EPMC3657717 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Yukimoto Naoya N Tsutsui Makusu M He Yuhui Y Shintaku Hirofumi H Tanaka Shoji S Kawano Satoyuki S Kawai Tomoji T Taniguchi Masateru M
Scientific reports 20130101
While fluorescent imaging has been extensively used for single-particle tracking, temporal and spatial resolution of the wide-field microscopy technology is not satisfactory for investigating fast-moving features. Here we report a method for probing nanometer-scale motion of an individual particle through a microstructured channel at sub-MHz by combining a resistive pulse technique to the optical sensing. We demonstrate unambiguous discriminations of translocation and non-translocation events in ...[more]