Ontology highlight
ABSTRACT:
SUBMITTER: de Messieres M
PROVIDER: S-EPMC4747024 | biostudies-literature | 2016 Jan
REPOSITORIES: biostudies-literature
de Messieres Michel M Ng Abby A Duarte Cornelio J CJ Remaley Alan T AT Lee Jennifer C JC
Analytical chemistry 20151214 1
Lipoproteins, such as high-density lipoprotein (HDL), low-density lipoprotein (LDL), and very-low density lipoprotein (VLDL), play a critical role in heart disease. Lipoproteins vary in size and shape as well as in their apolipoprotein content. Here, we developed a new experimental framework to study freely diffusing lipoproteins from human blood, allowing analysis of even the smallest HDL with a radius of 5 nm. In an easily constructed confinement chamber, individual HDL, LDL, and VLDL particle ...[more]