Ontology highlight
ABSTRACT:
SUBMITTER: Zhu Y
PROVIDER: S-EPMC3659047 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Zhu Ying Y Li Hong H Li Kehan K Zhao Xiaofeng X An Tai T Hu Xuemei X Park Jinsil J Huang Hao H Bin Yin Y Qiang Boqin B Yuan Jiangang J Peng Xiaozhong X Qiu Mengsheng M
PloS one 20130520 5
The timing and progression of axonal myelination are precisely controlled by intercellular interactions between neurons and glia in development. Previous in vitro studies demonstrated that Nectin like 4 (Necl-4, also known as cell adhesion molecule Cadm-4 or SynCAM-4) plays an essential role in axonal myelination by Schwann cells in the peripheral nervous system (PNS). However, the role of Necl-4 protein in axonal myelination in the developing central nervous system (CNS) has remained unknown. I ...[more]