Ontology highlight
ABSTRACT:
SUBMITTER: Cao RY
PROVIDER: S-EPMC3659118 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Cao Rui-Yuan RY Dong Da-Yong DY Liu Rui-Ju RJ Han Jian-Feng JF Wang Guang-Chuan GC Zhao Hui H Li Xiao-Feng XF Deng Yong-Qiang YQ Zhu Shun-Ya SY Wang Xiao-Yu XY Lin Fang F Zhang Fu-Jun FJ Chen Wei W Qin E-De ED Qin Cheng-Feng CF
PloS one 20130520 5
The emerging human enterovirus 71 (EV71) represents a growing threat to public health, and no vaccine or specific antiviral is currently available. Human intravenous immunoglobulin (IVIG) is clinical used in treating severe EV71 infections. However, the discovery of antibody dependent enhancement (ADE) of EV71 infection illustrates the complex roles of antibody in controlling EV71 infection. In this study, to identify the distinct role of each IgG subclass on neutralization and enhancement of EV ...[more]