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Long lived NMR signal in bone.

ABSTRACT: Solids and rigid tissues, such as bone, ligaments, and tendons, typically appear dark in MRI, which is due to the extremely short-lived proton nuclear magnetic resonance signals. This short lifetime is due to strong dipolar interactions between immobilized proton spins, which render it challenging to detect these signals with sufficient resolution and sensitivity. Here we show the possibility of exciting long-lived signals in cortical bone tissue with a signature consistent with that of bound water signals. It is further shown that dipolar coupling networks are an integral requirement for the excitation of these long-lived signals. The use of these signals could enhance the ability to visualize rigid tissues and solid samples with high resolution and sensitivity via MRI.

SUBMITTER: Zhang B

PROVIDER: S-EPMC3660456 | biostudies-literature | 2013 Jun

REPOSITORIES: biostudies-literature

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Long lived NMR signal in bone.

Zhang Boyang B Lee Jae-Seung JS Khitrin Anatoly A Jerschow Alexej A

Journal of magnetic resonance (San Diego, Calif. : 1997) 20130315

Solids and rigid tissues, such as bone, ligaments, and tendons, typically appear dark in MRI, which is due to the extremely short-lived proton nuclear magnetic resonance signals. This short lifetime is due to strong dipolar interactions between immobilized proton spins, which render it challenging to detect these signals with sufficient resolution and sensitivity. Here we show the possibility of exciting long-lived signals in cortical bone tissue with a signature consistent with that of bound wa ...[more]

PMID: 23562664

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