Ontology highlight
ABSTRACT:
SUBMITTER: Ngo HP
PROVIDER: S-EPMC3660893 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Ngo Ho Phuong Thuy HP Hong Seung Hye SH Oh Deok Kun DK Kang Lin Woo LW
Acta crystallographica. Section F, Structural biology and crystallization communications 20130430 Pt 5
Aldehyde dehydrogenase (ALDH) catalyses the oxidation of aldehydes using NAD(P)(+) as a cofactor. Most aldehydes are toxic at low levels. ALDHs are used to regulate metabolic intermediate aldehydes. The aldh gene from Bacillus cereus was cloned and the ALDH protein was expressed, purified and crystallized. A crystal of the ALDH protein diffracted to 2.6 Å resolution and belonged to the monoclinic space group P21, with unit-cell parameters a = 83.5, b = 93.3, c = 145.5 Å, β = 98.05°. Four protome ...[more]