Integral membrane proteins and bilayer proteomics.
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ABSTRACT:
SUBMITTER: Whitelegge JP
PROVIDER: S-EPMC3664232 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Publications
Integral membrane proteins and bilayer proteomics.
Analytical chemistry 20130219 5
Integral membrane proteins reside within the bilayer membranes that surround cells and organelles, playing critical roles in movement of molecules across them and the transduction of energy and signals. While their extreme amphipathicity presents technical challenges, biological mass spectrometry has been applied to all aspects of membrane protein chemistry and biology, including analysis of primary, secondary, tertiary, and quaternary structures as well as the dynamics that accompany functional ...[more]
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