Ontology highlight
ABSTRACT:
SUBMITTER: Zhou B
PROVIDER: S-EPMC3664360 | biostudies-literature | 2012 Jan
REPOSITORIES: biostudies-literature
Zhou Bin B Honor Leah B LB Ma Qing Q Oh Jin-Hee JH Lin Ruei-Zeng RZ Melero-Martin Juan M JM von Gise Alexander A Zhou Pingzhu P Hu Tianyuan T He Lingjuan L Wu Kai Hong KH Zhang Hui H Zhang Yuebo Y Pu William T WT
Journal of molecular and cellular cardiology 20110826 1
Myocardial infarction (MI) is one of the leading causes of morbidity and mortality world-wide. Whether endogenous repair and regenerative ability could be augmented by drug administration is an important issue for generation of novel therapeutic approach. Recently it was reported that in mice pretreated with thymosin beta 4 (TB4) and subsequently subjected to experimental MI, a subset of epicardial cells differentiated into cardiomyocytes. In clinical settings, epicardial priming with TB4 prior ...[more]