Ontology highlight
ABSTRACT:
SUBMITTER: Yin JY
PROVIDER: S-EPMC3670257 | biostudies-literature | 2013 Jun
REPOSITORIES: biostudies-literature
Carcinogenesis 20130207 6
RPA2 is a subunit of a trimeric replication protein A (RPA) complex important for DNA repair and replication. Although it is known that RPA activity is regulated by post-translational modification, whether RPA expression is regulated and the mechanism therein is currently unknown. eIF3a, the largest subunit of eIF3, is an important player in translational control and has been suggested to regulate translation of a subset of messenger RNAs important for tumorigenesis, metastasis, cell cycle progr ...[more]