Ontology highlight
ABSTRACT:
SUBMITTER: Hui M
PROVIDER: S-EPMC3672663 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Hui Mun M Cazet Aurélie A Nair Radhika R Watkins D Neil DN O'Toole Sandra A SA Swarbrick Alexander A
Breast cancer research : BCR 20130328 2
Despite the progress achieved in breast cancer screening and therapeutic innovations, the basal-like subtype of breast cancer (BLBC) still represents a particular clinical challenge. In order to make an impact on survival in this type of aggressive breast cancer, new targeted therapeutic agents are urgently needed. Aberrant activation of the Hedgehog (Hh) signalling pathway has been unambiguously tied to cancer development and progression in a variety of solid malignancies, and the recent approv ...[more]