Ontology highlight
ABSTRACT:
SUBMITTER: Maarouf CL
PROVIDER: S-EPMC3681206 | biostudies-literature | 2012 Sep
REPOSITORIES: biostudies-literature
Maarouf Chera L CL Beach Thomas G TG Adler Charles H CH Shill Holly A HA Sabbagh Marwan N MN Wu Terence T Walker Douglas G DG Kokjohn Tyler A TA Roher Alex E AE
Neurological research 20120901 7
<h4>Objectives</h4>Parkinson's disease (PD) afflicts approximately 1-2% of the population over 50 years of age. No cures or effective modifying treatments exist and clinical diagnosis is currently confounded by a lack of definitive biomarkers. We sought to discover potential biomarkers in the cerebrospinal fluid (CSF) of neuropathologically confirmed PD cases.<h4>Methods</h4>We compared postmortem ventricular CSF (V-CSF) from PD and normal control (NC) subjects using two-dimensional difference g ...[more]