Carbohydrate intake as a risk factor for biliary sludge and stones during pregnancy.

ABSTRACT:

Background

High carbohydrate intake has been linked to insulin resistance, obesity, and abnormal serum lipid profiles-conditions which favor gallstone formation.

Goals

The aim of this study was to evaluate the effect of dietary carbohydrate intake on incident gallbladder disease, defined as biliary sludge and stones, during pregnancy.

Study

We prospectively studied 3070 pregnant women who underwent serial gallbladder ultrasound during pregnancy and at 4 to 6 weeks postpartum. All women had at least 2 study ultrasounds for comparison. A semiquantitative food frequency questionnaire was completed by subjects in the early third trimester. Multivariate logistic regression was performed to assess the risk of incident gallbladder disease across quartiles total and individua

SUBMITTER: Wong AC 

PROVIDER: S-EPMC3681860 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature