Ontology highlight
ABSTRACT:
SUBMITTER: Kumar R
PROVIDER: S-EPMC3681954 | biostudies-literature | 2009 Jul
REPOSITORIES: biostudies-literature
Kumar Rajiv R Ohulchanskyy Tymish Y TY Roy Indrajit I Gupta Sandesh K SK Borek Carsten C Thompson Mark E ME Prasad Paras N PN
ACS applied materials & interfaces 20090701 7
We report a formulation of near-infrared (near-IR) phosphorescent polymeric nanomicelles and their use for in vivo high-contrast optical imaging, targeting, and detection of tumors in small animals. Near-IR phosphorescent molecules of Pt(II)-tetraphenyltetranaphthoporphyrin (Pt(TPNP)) were found to maintain their near-IR phosphorescence properties when encapsulated into phospholipid nanomicelles. The prepared phosphorescent micelles are of approximately 100 nm size and are highly stable in aqueo ...[more]