Dataset Information

Population genetics of 30 INDELs in populations of Poland and Taiwan.

ABSTRACT: The Investigator DIPplex(®) kit (Qiagen) contain components for the simultaneous amplification and analysis of 30 biallelic autosomal INDELs and amelogenin. The objective of this study was to estimate the diversity of the 30 markers in Polish (N P = 122) and Taiwanese (N T = 126) population samples and to evaluate their usefulness in forensic genetics. All amplicon lengths were shorter than 160 base pairs. The DIPplex genotype distributions showed no significant deviation from Hardy-Weinberg rule expectations (Bonferroni corrected) except for DLH39 in the Taiwanese population. Among the Poles and the Taiwanese the mean observed heterozygosity values are 0.4385 and 0.4079, and the combined matching probability values are 7.98 × 10(-14) and 1.22 × 10(-11), respectively. The investigated marker set has been confirmed as a potential extension to standard short tandem repeat-based kits or a separate informative system for individual identification and kinship analysis. Eight INDELs have been selected as possible ancestry informative single-nucleotide polymorphisms for further analyses.

SUBMITTER: Pepinski W

PROVIDER: S-EPMC3685699 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Population genetics of 30 INDELs in populations of Poland and Taiwan.

Pepinski Witold W Abreu-Glowacka Monica M Koralewska-Kordel Malgorzata M Michalak Eliza E Kordel Krzysztof K Niemcunowicz-Janica Anna A Szeremeta Michal M Konarzewska Magdalena M

Molecular biology reports 20130521 7

The Investigator DIPplex(®) kit (Qiagen) contain components for the simultaneous amplification and analysis of 30 biallelic autosomal INDELs and amelogenin. The objective of this study was to estimate the diversity of the 30 markers in Polish (N P = 122) and Taiwanese (N T = 126) population samples and to evaluate their usefulness in forensic genetics. All amplicon lengths were shorter than 160 base pairs. The DIPplex genotype distributions showed no significant deviation from Hardy-Weinberg rul ...[more]

PMID: 23690203

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Dataset Information

Population genetics of 30 INDELs in populations of Poland and Taiwan.

Publications

Population genetics of 30 INDELs in populations of Poland and Taiwan.

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