Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury.
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ABSTRACT:
SUBMITTER: Takeda N
PROVIDER: S-EPMC3688887 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury.
Takeda Norifumi N Jain Rajan R Li Deqiang D Li Li L Lu Min Min MM Epstein Jonathan A JA
PloS one 20130618 6
Taste buds are composed of a variety of taste receptor cell types that develop from tongue epithelium and are regularly replenished under normal homeostatic conditions as well as after injury. The characteristics of cells that give rise to regenerating taste buds are poorly understood. Recent studies have suggested that Lgr5 (leucine-rich repeat-containing G-protein coupled receptor 5) identifies taste bud stem cells that contribute to homeostatic regeneration in adult circumvallate and foliate ...[more]
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