Ontology highlight
ABSTRACT:
SUBMITTER: Barsheshet A
PROVIDER: S-EPMC3690290 | biostudies-literature | 2011 Oct
REPOSITORIES: biostudies-literature
Barsheshet Alon A Moss Arthur J AJ McNitt Scott S Polonsky Slava S Lopes Coeli M CM Zareba Wojciech W Robinson Jennifer L JL Ackerman Michael J MJ Benhorin Jesaia J Kaufman Elizabeth S ES Towbin Jeffrey A JA Vincent G Michael GM Qi Ming M Goldenberg Ilan I
Circulation. Cardiovascular genetics 20110810 5
<h4>Background</h4>Current clinical diagnosis of long-QT syndrome (LQTS) includes genetic testing of family members of mutation-positive patients. The present study was designed to assess the clinical course of individuals who are found negative for the LQTS-causing mutation in their families.<h4>Methods and results</h4>Multivariate Cox proportional hazards model was used to assess the risk for cardiac events (comprising syncope, aborted cardiac arrest [ACA], or sudden cardiac death [SCD]) from ...[more]