Ontology highlight
ABSTRACT:
SUBMITTER: Chen CH
PROVIDER: S-EPMC3690329 | biostudies-literature | 2012 Mar
REPOSITORIES: biostudies-literature
Chen Chi-Hua CH Gutierrez E D ED Thompson Wes W Panizzon Matthew S MS Jernigan Terry L TL Eyler Lisa T LT Fennema-Notestine Christine C Jak Amy J AJ Neale Michael C MC Franz Carol E CE Lyons Michael J MJ Grant Michael D MD Fischl Bruce B Seidman Larry J LJ Tsuang Ming T MT Kremen William S WS Dale Anders M AM
Science (New York, N.Y.) 20120301 6076
Surface area of the cerebral cortex is a highly heritable trait, yet little is known about genetic influences on regional cortical differentiation in humans. Using a data-driven, fuzzy clustering technique with magnetic resonance imaging data from 406 twins, we parceled cortical surface area into genetic subdivisions, creating a human brain atlas based solely on genetically informative data. Boundaries of the genetic divisions corresponded largely to meaningful structural and functional regions; ...[more]