Ontology highlight
ABSTRACT:
SUBMITTER: Marjamaa A
PROVIDER: S-EPMC3690340 | biostudies-literature | 2012 Jul
REPOSITORIES: biostudies-literature
Marjamaa Annukka A Oikarinen Lasse L Porthan Kimmo K Ripatti Samuli S Peloso Gina G Noseworthy Peter A PA Viitasalo Matti M Nieminen Markku S MS Toivonen Lauri L Kontula Kimmo K Peltonen Leena L Havulinna Aki S AS Jula Antti A O'Donnell Christopher J CJ Newton-Cheh Christopher C Perola Markus M Salomaa Veikko V
Heart rhythm 20120215 7
<h4>Background</h4>T-peak to T-end (TPE) interval on the electrocardiogram is a measure of myocardial dispersion of repolarization and is associated with an increased risk of ventricular arrhythmias. The genetic factors affecting the TPE interval are largely unknown.<h4>Objective</h4>To identify common genetic variants that affect the duration of the TPE interval in the general population.<h4>Methods</h4>We performed a genome-wide association study on 1870 individuals of Finnish origin participa ...[more]