Ontology highlight
ABSTRACT:
SUBMITTER: Medders KE
PROVIDER: S-EPMC3690763 | biostudies-literature | 2011 Jun
REPOSITORIES: biostudies-literature
Medders Kathryn E KE Kaul Marcus M
Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110201 2
Infection with human immunodeficiency virus-1 (HIV-1) often leads to HIV-associated neurocognitive disorders (HAND) prior to the progression to acquired immunodeficiency syndrome (AIDS). At the cellular level, mitogen-activated protein kinases (MAPK) provide a family of signal transducers that regulate many processes in response to extracellular stimuli and environmental stress, such as viral infection. Recently, evidence has accumulated suggesting that p38 MAPK plays crucial roles in various pa ...[more]