P38? overexpression in gliomas and its role in proliferation and apoptosis.
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ABSTRACT:
SUBMITTER: Yang K
PROVIDER: S-EPMC3695572 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
p38γ overexpression in gliomas and its role in proliferation and apoptosis.
Yang Kui K Liu Yunsheng Y Liu Zhixiong Z Liu Jinfang J Liu Xin X Chen Xin X Li Chuntao C Zeng Yu Y
Scientific reports 20130101
The objective of this study was to confirm the biological role of p38γ in human gliomas. The expression profiles of p38γ and hTERT in human glioma samples were detected by Western Blot and immunohistochemistry. RNA interference was performed in U251 cells by p38γ silencing. Cell proliferation and apoptosis were assayed by CCK-8 and flow cytometric analysis, and then RNA and protein expression levels were measured by real-time RT-PCR and Western Blot, respectively. Telomerase activity assays and ...[more]
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