Ontology highlight
ABSTRACT:
SUBMITTER: Dhillon PK
PROVIDER: S-EPMC3700351 | biostudies-literature | 2011 Dec
REPOSITORIES: biostudies-literature
Dhillon Preet K PK Penney Kathryn L KL Schumacher Fredrick F Rider Jennifer R JR Sesso Howard D HD Pollak Michael M Fiorentino Michelangelo M Finn Stephen S Loda Massimo M Rifai Nader N Mucci Lorelei A LA Giovannucci Edward E Stampfer Meir J MJ Ma Jing J
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110929 12
<h4>Background</h4>Adiponectin, an insulin-sensitizing adipokine, is inversely associated with adiposity and prostate cancer risk and progression. However, the role of genetic variation in the adiponectin (ADIPOQ) and receptor genes (ADIPOR1/R2) in prostate cancer is largely unknown.<h4>Methods</h4>In a nested case-control study of 1,286 cases and 1,267 controls within the Physicians' Health Study, we evaluated 29 common single-nucleotide polymorphisms (SNP) in ADIPOQ (n = 13), ADIPOR1 (n = 5), ...[more]