Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer.
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ABSTRACT:
SUBMITTER: Xiao X
PROVIDER: S-EPMC3702436 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Publications
Role of MUC20 overexpression as a predictor of recurrence and poor outcome in colorectal cancer.
Xiao Xiuying X Wang Lisha L Wei Ping P Chi Yayun Y Li Dali D Wang Qifeng Q Ni Shujuan S Tan Cong C Sheng Weiqi W Sun Menghong M Zhou Xiaoyan X Du Xiang X
Journal of translational medicine 20130620
<h4>Background</h4>Colorectal cancer (CRC) remains one of the most common cancers worldwide. We observed that MUC20 was significantly up-regulated in CRC patients with poor prognosis based on the microarray analysis. However, little is known about the role of MUC20 in CRC.<h4>Methods</h4>Microarray experiments were performed on the Affymetrix U133 plus 2.0 GeneChip Array. The protein and mRNA levels of MUC20 were examined by immunohistochemistry (IHC) and Real-Time quantitative PCR (RT-qPCR) in ...[more]
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