Ontology highlight
ABSTRACT:
SUBMITTER: Wu G
PROVIDER: S-EPMC3705411 | biostudies-literature | 2013 Apr
REPOSITORIES: biostudies-literature
Wu Guangwei G Lin Aiqun A Gu Qianqun Q Zhu Tianjiao T Li Dehai D
Marine drugs 20130423 4
A new chloro-trinoreremophilane sesquiterpene 1, three new chlorinated eremophilane sesquiterpenes 2-4, together with a known compound, eremofortine C (5), were isolated from an Antarctic deep-sea derived fungus, Penicillium sp. PR19N-1. Structures were established using IR, HRMS, 1D and 2D NMR techniques. In addition, the plausible metabolic network of these isolated products is proposed. Compound 1 showed moderate cytotoxic activity against HL-60 and A549 cancer cell lines. ...[more]