Ontology highlight
ABSTRACT:
SUBMITTER: Mostaco-Guidolin LB
PROVIDER: S-EPMC3709165 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Mostaço-Guidolin Leila B LB Ko Alex C-T AC Wang Fei F Xiang Bo B Hewko Mark M Tian Ganghong G Major Arkady A Shiomi Masashi M Sowa Michael G MG
Scientific reports 20130101
In this study we present an image analysis methodology capable of quantifying morphological changes in tissue collagen fibril organization caused by pathological conditions. Texture analysis based on first-order statistics (FOS) and second-order statistics such as gray level co-occurrence matrix (GLCM) was explored to extract second-harmonic generation (SHG) image features that are associated with the structural and biochemical changes of tissue collagen networks. Based on these extracted quanti ...[more]