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Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices.

ABSTRACT: We report a novel approach for effectively separating DNA molecules in free solution. The method uses a bare narrow open capillary without any sieving matrices to resolve a wide size-range of DNA fragments at efficiencies of more than a million plates per meter routinely.

SUBMITTER: Zhu Z

PROVIDER: S-EPMC3711670 | biostudies-literature | 2013 Apr

REPOSITORIES: biostudies-literature

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Resolving DNA at efficiencies of more than a million plates per meter using bare narrow open capillaries without sieving matrices.

Zhu Zaifang Z Liu Lei L Wang Wei W Lu Joann J JJ Wang Xiayan X Liu Shaorong S

Chemical communications (Cambridge, England) 20130401 28

We report a novel approach for effectively separating DNA molecules in free solution. The method uses a bare narrow open capillary without any sieving matrices to resolve a wide size-range of DNA fragments at efficiencies of more than a million plates per meter routinely. ...[more]

PMID: 23459665

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