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Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases.

ABSTRACT: Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide. SOD is classified into four metalloprotein isoforms, namely, Cu/Zn SOD, Mn SOD, Ni SOD and Fe SOD. The structural models of soybean SOD isoforms have not yet been solved. In this study, we describe structural models for soybean Cu/Zn SOD, Mn SOD and Fe SOD and provide insights into the molecular function of this metal-binding enzyme in improving tolerance to oxidative stress in plants.

SUBMITTER: Gopavajhula VR

PROVIDER: S-EPMC3715289 | biostudies-literature | 2013 Jul

REPOSITORIES: biostudies-literature

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Modeling and analysis of soybean (Glycine max. L) Cu/Zn, Mn and Fe superoxide dismutases.

Gopavajhula V Ramana VR Chaitanya K Viswanatha KV Akbar Ali Khan P P Shaik Jilani P JP Reddy P Narasimha PN Alanazi Mohammad M

Genetics and molecular biology 20130517 2

Superoxide dismutase (SOD, EC 1.15.1.1) is an important metal-containing antioxidant enzyme that provides the first line of defense against toxic superoxide radicals by catalyzing their dismutation to oxygen and hydrogen peroxide. SOD is classified into four metalloprotein isoforms, namely, Cu/Zn SOD, Mn SOD, Ni SOD and Fe SOD. The structural models of soybean SOD isoforms have not yet been solved. In this study, we describe structural models for soybean Cu/Zn SOD, Mn SOD and Fe SOD and provide ...[more]

PMID: 23885205

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