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Supramolecular metal displacement allows on-fluorescence analysis of manganese(II) in living cells.

ABSTRACT: Due to the importance of Mn(2+) ions in biological processes, it is of growing interest to develop protocols for analysis of Mn(2+) uptake and distribution in cells. A supramolecular metal displacement assay can provide ratiometric fluorescence detection of Mn(2+), allowing for quantitative and longitudinal analysis of Mn(2+) uptake in living cells.

SUBMITTER: Gruppi F

PROVIDER: S-EPMC3722360 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature

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Supramolecular metal displacement allows on-fluorescence analysis of manganese(II) in living cells.

Gruppi Francesca F Liang Jian J Bartelle Benjamin B BB Royzen Maksim M Turnbull Daniel H DH Canary James W JW

Chemical communications (Cambridge, England) 20121101 87

Due to the importance of Mn(2+) ions in biological processes, it is of growing interest to develop protocols for analysis of Mn(2+) uptake and distribution in cells. A supramolecular metal displacement assay can provide ratiometric fluorescence detection of Mn(2+), allowing for quantitative and longitudinal analysis of Mn(2+) uptake in living cells. ...[more]

PMID: 23023093

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