Dataset Information
DMEAS: DNA methylation entropy analysis software.
Ontology highlight
ABSTRACT: Summary
DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping results of bisulfite sequencing reads to extract DNA methylation patterns for contiguous CpG dinucleotides. It determines the DNA methylation level and calculates methylation entropy for genomic segments to enable the quantitative assessment of DNA methylation variations observed in cell populations.Availability and implementation
DMEAS program, user guide and all the testing data are freely available from http://sourceforge.net/projects/dmeas/files/
SUBMITTER: He J
PROVIDER: S-EPMC3722522 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Publications
DMEAS: DNA methylation entropy analysis software.
Bioinformatics (Oxford, England) 20130608 16
<h4>Summary</h4>DMEAS is the first user-friendly tool dedicated to analyze the distribution of DNA methylation patterns for the quantification of epigenetic heterogeneity. It supports the analysis of both locus-specific and genome-wide bisulfite sequencing data. DMEAS progressively scans the mapping results of bisulfite sequencing reads to extract DNA methylation patterns for contiguous CpG dinucleotides. It determines the DNA methylation level and calculates methylation entropy for genomic segm ...[more]
