The state of molecular biomarkers for the early detection of lung cancer.
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ABSTRACT:
SUBMITTER: Hassanein M
PROVIDER: S-EPMC3723112 | biostudies-literature | 2012 Aug
REPOSITORIES: biostudies-literature
Publications
The state of molecular biomarkers for the early detection of lung cancer.
Hassanein Mohamed M Callison J Clay JC Callaway-Lane Carol C Aldrich Melinda C MC Grogan Eric L EL Massion Pierre P PP
Cancer prevention research (Philadelphia, Pa.) 20120611 8
Using biomarkers to select the most at-risk population, to detect the disease while measurable and yet not clinically apparent has been the goal of many investigations. Recent advances in molecular strategies and analytic platforms, including genomics, epigenomics, proteomics, and metabolomics, have identified increasing numbers of potential biomarkers in the blood, urine, exhaled breath condensate, bronchial specimens, saliva, and sputum, but none have yet moved to the clinical setting. Therefo ...[more]
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