Ontology highlight
ABSTRACT:
SUBMITTER: Roxin A
PROVIDER: S-EPMC3723499 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PLoS computational biology 20130725 7
Long-term memories are likely stored in the synaptic weights of neuronal networks in the brain. The storage capacity of such networks depends on the degree of plasticity of their synapses. Highly plastic synapses allow for strong memories, but these are quickly overwritten. On the other hand, less labile synapses result in long-lasting but weak memories. Here we show that the trade-off between memory strength and memory lifetime can be overcome by partitioning the memory system into multiple reg ...[more]