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Cigarette smoking and onset of mood and anxiety disorders.


ABSTRACT: We examined the association between regular cigarette smoking and new onset of mood and anxiety disorders.We used logistic regression analysis to detect associations between regular smoking and new-onset disorders during the 3-year follow-up among 34 653 participants in the longitudinal US National Epidemiologic Survey on Alcohol and Related Conditions (2001-2005). We used instrumental variable methods to assess the appropriateness of these models.Regular smoking was associated with an increased risk of new onset of mood and anxiety disorders in multivariable analyses (Fdf = 5,61 = 11.73; P < .001). Participants who smoked a larger number of cigarettes daily displayed a trend toward greater likelihood of new-onset disorders. Age moderated the association of smoking with most new-onset disorders. The association was mostly statistically significant and generally stronger in participants aged 18 to 49 years but was smaller and mostly nonsignificant in older adults.Our finding of a stronger association between regular cigarette smoking and increased risk of new-onset mood and anxiety disorders among younger adults suggest the need for vigorous antismoking campaigns and policy initiatives targeting this age group.

SUBMITTER: Mojtabai R 

PROVIDER: S-EPMC3726564 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature

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Cigarette smoking and onset of mood and anxiety disorders.

Mojtabai Ramin R   Crum Rosa M RM  

American journal of public health 20130117 9


<h4>Objectives</h4>We examined the association between regular cigarette smoking and new onset of mood and anxiety disorders.<h4>Methods</h4>We used logistic regression analysis to detect associations between regular smoking and new-onset disorders during the 3-year follow-up among 34 653 participants in the longitudinal US National Epidemiologic Survey on Alcohol and Related Conditions (2001-2005). We used instrumental variable methods to assess the appropriateness of these models.<h4>Results</  ...[more]

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