?2-Adrenergic receptor solutions for structural biology analyzed with microscale NMR diffusion measurements.

ABSTRACT: Microcoil NMR measurements were performed to determine the final composition of solutions of the ?(2)-adrenergic receptor (?(2)AR) reconstituted with a detergent and to study the hydrodynamic properties of the detergent micelles containing ?(2)AR. Standards are established for the reproducible preparation of G-protein-coupled receptor solutions for crystallization trials and solution NMR studies.

SUBMITTER: Horst R 

PROVIDER: S-EPMC3729229 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature