Ontology highlight
ABSTRACT:
SUBMITTER: Ireland R
PROVIDER: S-EPMC3729262 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Journal of immunology (Baltimore, Md. : 1950) 20130701 3
Induction of innate immunity is essential for host survival of infection. Evasion and inhibition of innate immunity constitute a strategy used by pathogens, such as the highly virulent bacterium Francisella tularensis, to ensure their replication and transmission. The mechanism and bacterial components responsible for this suppression of innate immunity by F. tularensis are not defined. In this article, we demonstrate that lipids enriched from virulent F. tularensis strain SchuS4, but not attenu ...[more]