Current therapeutic strategies and novel approaches in osteosarcoma.
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ABSTRACT:
SUBMITTER: Ando K
PROVIDER: S-EPMC3730336 | biostudies-literature | 2013 May
REPOSITORIES: biostudies-literature
Publications
Current therapeutic strategies and novel approaches in osteosarcoma.
Ando Kosei K Heymann Marie-Françoise MF Stresing Verena V Mori Kanji K Rédini Françoise F Heymann Dominique D
Cancers 20130524 2
Osteosarcoma is the most frequent malignant primary bone tumor and a main cause of cancer-related death in children and adolescents. Although long-term survival in localized osteosarcoma has improved to about 60% during the 1960s and 1970s, long-term survival in both localized and metastatic osteosarcoma has stagnated in the past several decades. Thus, current conventional therapy consists of multi-agent chemotherapy, surgery and radiation, which is not fully adequate for osteosarcoma treatment. ...[more]
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