Ontology highlight
ABSTRACT:
SUBMITTER: Mollica V
PROVIDER: S-EPMC7352972 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Mollica Veronica V Rizzo Alessandro A Montironi Rodolfo R Cheng Liang L Giunchi Francesca F Schiavina Riccardo R Santoni Matteo M Fiorentino Michelangelo M Lopez-Beltran Antonio A Brunocilla Eugenio E Brandi Giovanni G Massari Francesco F
Cancers 20200602 6
Urothelial carcinoma (UC) is a frequent cause of cancer-related deaths worldwide. Metastatic UC has been historically associated with poor prognosis, with a median overall survival of approximately 15 months and a 5-year survival rate of 18%. Although platinum-based chemotherapy remains the mainstay of medical treatment for patients with metastatic UC, chemotherapy clinical trials produced modest benefit with short-lived, disappointing responses. In recent years, the better understanding of the ...[more]