Ontology highlight
ABSTRACT:
SUBMITTER: Yao NY
PROVIDER: S-EPMC3732650 | biostudies-literature | 2009 Jun
REPOSITORIES: biostudies-literature
Yao Nina Y NY O'Donnell Mike M
Current opinion in cell biology 20090416 3
Replisomes are multiprotein complexes that unzip the parental helix and duplicate the separated strands during genome replication. The antiparallel structure of DNA poses unique geometric constraints to the process, and the replisome has evolved unique dynamic features that solve this problem. Interestingly, the solution to duplex DNA replication has been co-opted to solve many other important problems that replisomes must contend with during the duplication of long chromosomes. For example, alo ...[more]