Ontology highlight
ABSTRACT:
SUBMITTER: Wojczynski MK
PROVIDER: S-EPMC3733595 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
BMC medical genetics 20130719
<h4>Background</h4>Coronary heart disease (CHD) is the major cause of death in the United States. Coronary artery calcification (CAC) scores are independent predictors of CHD. African Americans (AA) have higher rates of CHD but are less well-studied in genomic studies. We assembled the largest AA data resource currently available with measured CAC to identify associated genetic variants.<h4>Methods</h4>We analyzed log transformed CAC quantity (ln(CAC + 1)), for association with ~2.5 million sing ...[more]