Modulation of the current signatures of DNA abasic site adducts in the ?-hemolysin ion channel.
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ABSTRACT:
SUBMITTER: An N
PROVIDER: S-EPMC3738171 | biostudies-literature | 2012 Dec
REPOSITORIES: biostudies-literature
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Modulation of the current signatures of DNA abasic site adducts in the α-hemolysin ion channel.
An Na N White Henry S HS Burrows Cynthia J CJ
Chemical communications (Cambridge, England) 20121017 93
Electrical current signatures of DNA adducts were investigated during immobilization of strands inside the membrane-bound α-hemolysin ion channel. The current blockages produced by these adducts were found to depend on both size and shape, providing insights into the DNA-protein interactions and the size limitation of bulky adducts to be translocated. ...[more]
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