Ontology highlight
ABSTRACT:
SUBMITTER: Weiner BE
PROVIDER: S-EPMC3738745 | biostudies-literature | 2013 Jul
REPOSITORIES: biostudies-literature
Weiner Brian E BE Woetzel Nils N Karakaş Mert M Alexander Nathan N Meiler Jens J
Structure (London, England : 1993) 20130530 7
Membrane protein structure determination remains a challenging endeavor. Computational methods that predict membrane protein structure from sequence can potentially aid structure determination for such difficult target proteins. The de novo protein structure prediction method BCL::Fold rapidly assembles secondary structure elements into three-dimensional models. Here, we describe modifications to the algorithm, named BCL::MP-Fold, in order to simulate membrane protein folding. Models are built i ...[more]