Ontology highlight
ABSTRACT:
SUBMITTER: Suhanovsky MM
PROVIDER: S-EPMC4424165 | biostudies-literature | 2015 May
REPOSITORIES: biostudies-literature
Suhanovsky Margaret M MM Teschke Carolyn M CM
Virology 20150408
For many (if not all) bacterial and archaeal tailed viruses and eukaryotic Herpesvirdae the HK97-fold serves as the major architectural element in icosahedral capsid formation while still enabling the conformational flexibility required during assembly and maturation. Auxiliary proteins or Δ-domains strictly control assembly of multiple, identical, HK97-like subunits into procapsids with specific icosahedral symmetries, rather than aberrant non-icosahedral structures. Procapsids are precursor st ...[more]