Ontology highlight
ABSTRACT:
SUBMITTER: Stalmans S
PROVIDER: S-EPMC3739727 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Stalmans Sofie S Wynendaele Evelien E Bracke Nathalie N Gevaert Bert B D'Hondt Matthias M Peremans Kathelijne K Burvenich Christian C De Spiegeleer Bart B
PloS one 20130809 8
Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several problematic cargoes, like e.g. plasmid DNA and (si)RNA, opening doors for new therapeutics. Although several hundreds of CPPs are already described in the literature, only a few commercial applications of CPPs are currently available. Cellular uptake studies of these peptides suffer from inconsistencies in used techniques and other experime ...[more]