Ontology highlight
ABSTRACT:
SUBMITTER: Bose N
PROVIDER: S-EPMC3740326 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Bose Nandita N Chan Anissa S H AS Guerrero Faimola F Maristany Carolyn M CM Qiu Xiaohong X Walsh Richard M RM Ertelt Kathleen E KE Jonas Adria Bykowski AB Gorden Keith B KB Dudney Christine M CM Wurst Lindsay R LR Danielson Michael E ME Elmasry Natalie N Magee Andrew S AS Patchen Myra L ML Vasilakos John P JP
Frontiers in immunology 20130812
The immunomodulatory properties of yeast β-1,3/1,6 glucans are mediated through their ability to be recognized by human innate immune cells. While several studies have investigated binding of opsonized and unopsonized particulate β-glucans to human immune cells mainly via complement receptor 3 (CR3) or Dectin-1, few have focused on understanding the binding characteristics of soluble β-glucans. Using a well-characterized, pharmaceutical-grade, soluble yeast β-glucan, this study evaluated and cha ...[more]