Ontology highlight
ABSTRACT:
SUBMITTER: Lee JH
PROVIDER: S-EPMC3744537 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Lee Jeong-Hwan JH Park Da-Young DY Lee Kyung-Jin KJ Kim Young-Kwan YK So Yang-Kang YK Ryu Jae-Sung JS Oh Seung-Han SH Han Yeon-Soo YS Ko Kinarm K Choo Young-Kug YK Park Sung-Joo SJ Brodzik Robert R Lee Kyoung-Ki KK Oh Doo-Byoung DB Hwang Kyung-A KA Koprowski Hilary H Lee Yong Seong YS Ko Kisung K
PloS one 20130815 8
Plant genetic engineering, which has led to the production of plant-derived monoclonal antibodies (mAb(P)s), provides a safe and economically effective alternative to conventional antibody expression methods. In this study, the expression levels and biological properties of the anti-rabies virus mAb(P) SO57 with or without an endoplasmic reticulum (ER)-retention peptide signal (Lys-Asp-Glu-Leu; KDEL) in transgenic tobacco plants (Nicotiana tabacum) were analyzed. The expression levels of mAb(P) ...[more]