Ontology highlight
ABSTRACT:
SUBMITTER: Serganov A
PROVIDER: S-EPMC3744878 | biostudies-literature | 2012 Jun
REPOSITORIES: biostudies-literature
Current opinion in structural biology 20120512 3
Regulatory mRNAs elements termed riboswitches respond to elevated concentrations of cellular metabolites by modulating expression of associated genes. Riboswitches attain their high metabolite selectivity by capitalizing on the intrinsic tertiary structures of their sensor domains. Over the years, riboswitch structure and folding have been amongst the most researched topics in the RNA field. Most recently, novel structures of single-ligand and cooperative double-ligand sensors have broadened our ...[more]