Ontology highlight
ABSTRACT:
SUBMITTER: Lynch SA
PROVIDER: S-EPMC1858662 | biostudies-other | 2007 Feb
REPOSITORIES: biostudies-other
Lynch Sean A SA Desai Shawn K SK Sajja Hari Krishna HK Gallivan Justin P JP
Chemistry & biology 20070201 2
Riboswitches are RNA-based genetic control elements that regulate gene expression in a ligand-dependent fashion without the need for proteins. The ability to create synthetic riboswitches that control gene expression in response to any desired small-molecule ligand will enable the development of sensitive genetic screens that can detect the presence of small molecules, as well as designer genetic control elements to conditionally modulate cellular behavior. Herein, we present an automated high-t ...[more]