Lipid metabolism in Trypanosoma brucei.
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ABSTRACT:
SUBMITTER: Smith TK
PROVIDER: S-EPMC3744938 | biostudies-literature | 2010 Aug
REPOSITORIES: biostudies-literature
Publications
Lipid metabolism in Trypanosoma brucei.
Smith Terry K TK Bütikofer Peter P
Molecular and biochemical parasitology 20100409 2
Trypanosoma brucei membranes consist of all major eukaryotic glycerophospholipid and sphingolipid classes. These are de novo synthesized from precursors obtained either from the host or from catabolised endocytosed lipids. In recent years, substantial progress has been made in the molecular and biochemical characterisation of several of these lipid biosynthetic pathways, using gene knockout or RNA interference strategies or by enzymatic characterization of individual reactions. Together with the ...[more]
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