HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection.
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ABSTRACT:
SUBMITTER: Deng CQ
PROVIDER: S-EPMC3746388 | biostudies-literature | 2013 Aug
REPOSITORIES: biostudies-literature
Publications
HMGB1 gene polymorphisms in patients with chronic hepatitis B virus infection.
Deng Chun-Qing CQ Deng Guo-Hong GH Wang Yu-Ming YM
World journal of gastroenterology 20130801 31
<h4>Aim</h4>To characterize high mobility group box chromosomal protein 1 (HMGB1) polymorphisms in patients infected with hepatitis B virus (HBV) and determine the different patterns in patient subgroups.<h4>Methods</h4>A total of 1495 unrelated Han Chinese HBV carriers were recruited in this hospital-based case-control study. The HMGB1 1176 G/C polymorphism was genotyped by polymerase chain reaction-restriction fragment length polymorphism assay.<h4>Results</h4>A significant association was obs ...[more]
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