Ontology highlight
ABSTRACT:
SUBMITTER: Byrum SD
PROVIDER: S-EPMC3748992 | biostudies-literature | 2013 Mar
REPOSITORIES: biostudies-literature
Journal of proteomics & bioinformatics 20130301 3
Molecular pathways regulating melanoma initiation and progression are potential targets of therapeutic development for this aggressive cancer. Identification and molecular analysis of these pathways in patients has been primarily restricted to targeted studies on individual proteins. Here, we report the most comprehensive analysis of formalin-fixed paraffin-embedded human melanoma tissues using quantitative proteomics. From 61 patient samples, we identified 171 proteins varying in abundance amon ...[more]