Ontology highlight
ABSTRACT:
SUBMITTER: Antonini D
PROVIDER: S-EPMC3749490 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
Antonini Dario D Sibilio Annarita A Dentice Monica M Missero Caterina C
Frontiers in endocrinology 20130822
Skin is the largest organ of the human body and plays a key role in protecting the individual from external insults. The barrier function of the skin is performed primarily by the epidermis, a self-renewing stratified squamous epithelium composed of cells that undergo a well-characterized and finely tuned process of terminal differentiation. By binding to their receptors thyroid hormones (TH) regulate epidermal cell proliferation, differentiation, and homeostasis. Thyroid dysfunction has multipl ...[more]