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Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3.

ABSTRACT: A presumptive chromosomal cephalosporinase (pI, 9.0) from a clinical strain of Acinetobacter genomic species 3 (AG3) is reported. The nucleotide sequence of this beta-lactamase shows for the first time the gene encoding an AmpC enzyme in AG3. In addition, the biochemical properties of the novel AG3 AmpC beta-lactamase are reported

SUBMITTER: Beceiro A

PROVIDER: S-EPMC375293 | biostudies-literature | 2004 Apr

REPOSITORIES: biostudies-literature

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Molecular characterization of the gene encoding a new AmpC beta-lactamase in a clinical strain of acinetobacter genomic species 3.

Beceiro Alejandro A Dominguez Lourdes L Ribera Anna A Vila Jordi J Molina Francisca F Villanueva Rosa R Eiros Jose Maria JM Bou German G

Antimicrobial agents and chemotherapy 20040401 4

A presumptive chromosomal cephalosporinase (pI, 9.0) from a clinical strain of Acinetobacter genomic species 3 (AG3) is reported. The nucleotide sequence of this beta-lactamase shows for the first time the gene encoding an AmpC enzyme in AG3. In addition, the biochemical properties of the novel AG3 AmpC beta-lactamase are reported ...[more]

PMID: 15047547

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Comparative phosphoproteomics reveals the role of AmpC β-lactamase phosphorylation in the clinical imipenem-resistant strain Acinetobacter baumannii SK17 (MaxQuant 1.3 and 1.4)

Project description:Nosocomial outbreaks of infections caused by multidrug-resistant Acinetobacter baumannii have emerged as a serious threat to human health. The phosphoproteomics of pathogenic bacteria have been investigated for their role in virulence regulation networks. In this study, we analyzed the phosphoproteomics of two clinical isolates of A. baumannii: imipenem-sensitive strain SK17-S and -resistant strain SK17-R.

2015-10-27 | PXD002033 | Pride

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